PHD THESIS POLYHYDROXYALKANOATES

This thesis presents the first thorough analysis of PHAs surface properties, which may be helpful to better understand already used PHA-based biomaterials. Polyhydroxyoctanoate P 3HO , a medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina. Both the neat and composite films were flexible and elastomeric in nature. Imaging internal features of whole, unfixed bacteria Thomson, N. PHUE scaffolds were prepared using the Langmuir monolayer technique, which enabled a control over the polymer molecular organization, and produced stable two-dimensional 2D films on the air-water interface.

For example, bone is a natural composite of an organic matrix collagen and inorganic crystals calcium phosphate. In vitro degradation studies revealed the films both neat and composite underwent hydrolytic degradation which started at the surface and that aged with time. Imaging internal features of whole, unfixed bacteria. Production of Polyhydroxyalkanoates from Bacillus cereus SPV under different nutrient limiting conditions. Materials Science and Engineering R:

Highly elastomeric poly 3-hydroxyoctanoate based natural polymer composite for enhanced keratinocyte regeneration.

Such a combination of two components, which alone have thesie like poor load bearing of collagen and brittleness of calcium phosphate, enables bone to accept high load and fulfill its functions in the body. Imaging internal features of whole, unfixed bacteria.

Industrial production of PHA

Appl Environ Microbiol The homopolymer P 3HO was also studied as a potential biomaterial for medical applications. Enviado por Alailson flag Denunciar. Nutrient limitations play a pivotol role in PHA production, hence studies were carried out on polyhydroxyalkanoafes effects of nitrogen, phosphorous, potassium and sulphate limitations on the short chain length, scl-PHA C3-C5 carbon chain length accumulation by B.

  LANCIA THESIS DE VANZARE OLX

Polyhydroxyoctanoate P 3HOa medium chain length polyhydroxyalkanoate homopolymer from Pseudomonas mendocina Rai, R. This thesis presents polyhydroyxalkanoates first thorough analysis of PHAs surface properties, which may be helpful to better understand already used PHA-based biomaterials.

Biosynthesis of polyhydroxyalkanoates and its medical applications : WestminsterResearch

The organism showed interesting mcl-PHA biosynthetic capability. Microbial biosynthesis of PHAs and its applications. Both the neat and composite films were able to support the attachment, growth and proliferation of the HaCaT cells.

Medium chain length polyhydroxyalkanoates, promising new biomedical materials for the future Rai, R. Medium chain length polyhydroxyalkanoates, promising new biomedical materials for the future.

For this application, a large amount of PHA is needed. Modification of P 3HO was also carried out. For low-value-added applications, PHA is mainly a target for environmentally friendly packaging purposes.

phd thesis polyhydroxyalkanoates

The interactions were highly reliant on the lipid head group size and orientation at the free water surface, and are interpreted considering intra- and intermolecular forces between lipid and polymer molecules. Furthermore, the results may be also of interest for applications where properties of polyhydroxyalkanoattes, molecularly organized films are crucial for the product design and performance, such as sensors.

A detailed study on the effects of different extraction methods on the yield, molecular weight, thermal properties and thessi LPS content of P 3HO was carried out. Production of polyhydroxyalkanoates and their biomedical applications Roy, I. In vitro degradation studies revealed the films both neat and composite underwent hydrolytic degradation which started at the surface and that aged with time.

  LITERARY ESSAY RAYMONDS RUN

Biosynthesis of polyhydroxyalkanoates and its medical applications

SCI, London 10 Dec Dawes ED ed Novel biodegradable microbial polymers. Biodegradable polymers and green chemistry Royal Society of Chemistry. Thus, by combining components with complementary properties, materials with improved or novel properties could be produced. The organic-inorganic composite materials were obtained by using one-component polymer or lipid and mixed polymer-lipid monomolecular films as templates influencing the growth of calcium phosphate.

However the result could polyhjdroxyalkanoates be confirmed with NMR.

phd thesis polyhydroxyalkanoates

Imaging internal features of whole, unfixed bacteria Thomson, N. This has been pointed out in Chapter 5: References Akiyama M, Tsuge T, Doi Y Environmental life cycle comparison of polyhydroxyalkano- ates produced from renewable carbon resources by bacterial fermentation. This is the first time that an absolute homopolymer of P 3HO has been produced.

The films showed signs of polymer ageing and underwent slow hydrolytic degradation possibly because of the cross linked P 3HO chains. Journal of Applied Polymer Science. The study of PHA interactions with lipids provides additional insights for pklyhydroxyalkanoates of e. For example, bone is a natural composite of an organic matrix collagen and inorganic crystals calcium phosphate.