The aim of the study was to measure airway patency objectively during dexmedetomidine sedation under radiographic guidance in spontaneously breathing pediatric patients scheduled for cardiac catheterization procedures. There are little pharmacokinetic data regarding newborns who have immature drug metabolizing capacity and who are at risk for reduced dexmedetomidine clearance and drug toxicity. The DEX group received a loading dose of 0. Anesthesia was maintained with target-controlled infusion TCI of propofol and remifentanyl. The effect on normal tissues and the clinical use of intraoperative radiotherapy in several Kind of cancer is studied. Dexmedetomidine ; an adjuvant drug for fast track technique in pediatric cardiac surgery.

Activation of intraoperative epileptiform activity may also be required if there are no spontaneous discharges. The anesthetic management of neurosurgical patients who possess these contraindications but would be optimally treated by an awake procedure remains unclear. The pain is more intense as the local anesthetic wears off. Investigators who were not directly involved in the care of the patient prepared the infusions, while the dental surgeon, anesthetist, and the patients were blinded to the group allocation and drugs given. Cost of dexmedetomidine therapy and debate as to the proper duration of use has brought its use to the forefront of discussion. Anaesthesia was induced with propofol and maintained with isoflurane.

An appropriate therapeutic decision. After baseline MAC determination, dogs were administered two incremental loading and infusion doses of either dexmedetomidine 1.

Severe cardiovascular responses occur during trans-sphenoidal resection TSR of the pituitary adenoma despite adequate depth of anesthesia. The average HR decreased from beats per minute to The case report describes the features and outlines the treatment strategy adopted. The median age was 16 months range, 0.


Dexmedetomidine could enhance tyesis satisfaction in Trans-sphenoidal resection of pituitary adenoma.

intraoperative dexmedetomidine infusion: Topics by

Intra-operativelythey were assessed for sedation, hemodynamic changes, respiratory efficiency, and side effects. Perioperative thoracic epidural analgesia for thoracotomy. Transsphenoidal approach to pituitary tumors is a commonly performed procedure with the advantage of a rapid midline access to the sella with minimal complications. Ropivacaine, 15 ml of 0.

dexmedetomidine thesis topics

The mean heart rate was significantly lower in group D compared to groups E and Dexmedeetomidine at all times of measurement P infusion of study drugs. Adequate preoperative visits and counseling of patient and parents regarding course and nature of events along with well-planned intraoperative management are of utmost importance in a pediatric age group for successful intraoperative awake craniotomy.

dexmedetomidine thesis topics

Patients were tehsis if they had a clinical history or electrocardiographic evidence of heart block, ischemic heart disease, asthma, sleep apnea syndrome, impaired liver or renal function, known psychiatric illness, diabetes, facial pain, psychological problems, smoking history, or chronic use of sedative or analgesic drugs or opioids.

Although the plasma albumin concentrations The patient characteristics and operation data of both groups are shown in Table 1.

Choosing a Thesis Topic – SMS Anaesthesia Thesis Centre

Dexmedetomidine is recommended for the sedation of adult ICU patients who need a sedation level not deeper than arousal in response to verbal stimulation corresponding to Richmond Agitation-Sedation Scale 0 to Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions.

On Day 14, the mean concentration was between Analgesia was evaluated by clinical signs and inhalational anesthetic inspired concentration was evaluated by anesthetic gases analysis during surgery.

Alleviating stress response to tracheal extubation in neurosurgical patients: Most common intraoperative complication was seizures; observed in five patients A comparative study of two infusion doses of dexmedetomidine.


dexmedetomidine thesis topics

The primary endpoint was creatinine clearance. All samples were tested in duplicate.

Oxidative Medicine and Cellular Longevity

The discrepancy can dexmedetomidind explained on the basis that there have been no earlier studies which have established the dose equivalence of fentanyl and dexmedetomidine.

Rats were subjected to 1 hour middle cerebral artery occlusion and a 2-hour reperfusion. Neuroprotective effects of dexmedetomidine have been reported in various brain injury models.

Delayed awakening might be associated with this treatment. The aim of the study was to determine whether or not dexmedetomidine- DEX- based intravenous infusion in dental implantation can provide better sedation and postoperative analgesia via suppressing postoperative inflammation and oxidative stress. Gynaecological, Orthopaedic or Specific surgery eg.

Group RD was administered 17 ml of 0. This was a retrospective cohort study of adult patients who received dexmedetomidine for ICU sedation while on mechanical ventilation at a bed not-for-profit community hospital. Full-term neonates and infants requiring mechanical ventilation after open heart surgery received dexmedetomidune in a dose-escalation study. Effect of the perioperative infusion of dexmedetomidine on chronic pain after breast surgery.

The mean duration of mechanical ventilation with dexmedetomidine was numerically shorter than with propofol and significantly shorter than with midazolam.